okay so let me give fake names to the important ppl in this story.
friend A friend K person L person V
so friend A and I have known each other for a while, and then we became friends with friend K. Friend K, L, V have a class together and right after, friend A, K, V have another class together.
I have been having a lot of issues with friend A that were minor but I was too scared to talk to her because i didn’t want to lose her. So, I would ask friend K about input. L&V apparently didn’t like friend A and I wouldn’t shit talk to her to them but I would talk about my issues hoping they would help too, especially after they showed vulnerability to me about other issues they had, I thought I would open to them too. It got messy, friend K felt awkward about this all and they started to make me feel like the bad guy about my situation with friend A, peer pressuring me in a negative way to talk to her. I started getting overwhelmed and crappy and I ultimately just spoke to friend A and it went way better than expected.
L&V were causing drama, instigating, I didn’t know them like that and I laid my boundaries with them. I also cut them off because I felt like they would have been negative additions to my life. I had to also be stern with friend K because she was talking a lot about things that didn’t make sense to my character, and so we took a break from talking to each other for almost two weeks.
I had class again today, I missed the first lecture because I was too nervous about L&V talking about me, which they did during the 15 min break with friend K.
V told friend K she had send me the day before and smiled to me but that I didn’t say hi. I genuinely didn’t see that person but friend K made it seem like I was a bad person. Friend K and I had an hour talk, I told her my rights and wrongs about everything that happened and what I wanted to change moving forward and how I felt about how she behaved. I felt like she kept pointing fingers at me and painting me in a negative way, not an effective talk. She said she wants to take a longer break from me. I just feel so dumb? I feel like I was trying to talk maturely and i just let her kind of paint this narrative of me?

Warren Buffett states, “The stock market is a vehicle for moving money from the impatient to the patient.” That is usually true, but if you are patient and knowledgeable about investing in stocks, you may profit and develop wealth. A stock market is a fascinating location to learn about money management.
The stock market is like a roller coaster, and the trip is always exciting and terrifying. Nevertheless, the allure of the stock market draws millions of investors and generates wealth. People interested in Indian stock markets usually analyze their fundamentals and technicalities.
Facts about the stock market that can help you become a better investor
Only a Small Percentage of Ordinary People Invest
Despite being the world’s oldest and largest stock exchange, barely 2.5% of the general populace invests in the stock market. This figure is insufficient, and more individuals should grasp the value of financial independence. Only eight crore people out of a total population of 132 crore invest in mutual funds. Only 12% of India’s GDP comprises Indian mutual fund market assets.
The BSE Is the Largest and Oldest Stock Exchange
The Bombay Stock Exchange, or BSE, is the world’s largest stock exchange. The BSE has the most firms listed (5,500), making it the world’s largest stock market. The Bombay Stock Exchange was founded in 1875 by a trader called Premchand Roychand and is the oldest in Asia. As a result of his success in the stockbroking industry, he was dubbed the Cotton King, the Bullion King, and the Big Bull. In addition to the BSE, India has 23 other stock exchanges.
Stocks Have Existed for a Long Time
For starters, stocks have been around for far longer than you may believe. Suppose you define a stock market as a regulated marketplace where individuals can buy and sell investments. In that case, you can trace its origins back to the 11th century in France when agricultural loans were traded, and the 16th century in Belgium, when a more sophisticated debt market existed. The Dutch East India Company, formed in 1602 and involved in trading between Asia and Europe, appears to have had the first publicly listed stock. Its stock was traded on the Amsterdam Stock Exchange.
After a Crash, the Stock Market Usually Recovers Quickly
Many investors fear stock market corrections and crashes, but it’s pointless to hope they don’t happen since they will. They will vary in strength and length, but the news isn’t all that awful on average. Capital Group examined stock market performance from 1950 to 2019 and discovered that 10% or more pullbacks occurred roughly once a year and lasted an average of 112 days. Even recoveries lasting twice as long as seven months would be preferable. These are merely averages, and anything may happen at any time, but keep in mind that the stock market recovers from most major declines very soon. Long-term investors can benefit significantly from market dips.
Rule of 72
When a newbie initially begins investing, the first question he usually has is how long it will take to double his money. The time necessary to double the investment is computed using the rule of 72, which requires a defined and stable interest rate. Divide the rate of return by 72 to get an estimate of the return on investment. Let us illustrate using an example: say you invest Rs 500,000 at an 8% rate. So 72/8 = 9, implying your investment will double in 9 years.
Mumbai Has the Highest Number of Demat Accounts
In India, there was 3.38 lakh Demat accounts as of September 2018. According to November 2018 SEBI bulletin figures, there are 177 lahks NSDL and 161 lahks CSDL accounts. Mumbai has the most Demat accounts, whereas Gujarat has the second-highest number in the state.
The World’s Most Expensive Stock
Berkshire Hathaway is the most expensive stock in the world. A single share of the corporation costs more than Rs 2 crore. Berkshire Hathaway Inc. is an American multinational conglomerate headquartered in Omaha, Nebraska. The corporation is the world’s third-biggest public company and the world’s largest financial services company by revenue. The Chairman is legendary investor Warren Buffett. The company’s share was sold for $313,350.00 on February 1, 2019, making it one of the most expensive scrips in the world. It is because the firm has never had a stock split and has only paid dividends once. On October 23, 2006, the company’s stock reached $100,000 for the first time.
Even Pirates Have Their Own Stock Exchange
Sure, there are stock markets for shares of corporations that provide various products and services, as well as bond markets for investors to swap debt obligations. But not long ago, even pirates had a stock market. In 2011, the Wall Street Journal reported on it: “In 2009, the world’s first pirate stock market was formed in Harardheere, Somalia, about 250 miles northeast of Mogadishu. The exchange, open 24 hours a day, permits investors to benefit from ransoms collected on the high seas, which may reach $10 million for successful attacks on Western commercial boats.”
The aforementioned fascinating facts about the stock market demonstrate that it can develop. We hope these little-known facts pique your interest in the stock market. The more you study the financial market, the more fascinated you may be by how fascinating it is. And the more knowledgeable you get, the faster your portfolio may expand.
If you want to invest in the stock market, Bharti Share Market can assist you in creating a Demat account and educate you on how to do it properly. So visit us right now to begin benefiting from the stock market!

https://doi.org/10.1002/mrm.29648
https://pubmed.ncbi.nlm.nih.gov/36971349

Abstract

PURPOSE

To monitor the metabolic turnover of β-hydroxybutyrate (BHB) oxidation using² H-MRS in conjunction with intravenous administration of² H labeled BHB.

METHODS

Nine-month-old mice were infused with [3,4,4,4]-² H 4 -BHB (d 4 -BHB, 3.11 g/kg) through the tail vein using a bolus variable infusion rate for a period of 90 min. The labeling of downstream cerebral metabolites from the oxidative metabolism of d 4 -BHB was monitored using² H-MRS spectra acquired with a home-built² H surface coil on a 9.4T preclinical MR scanner with a temporal resolution of 6.25 min. An exponential model was fit to the BHB and glutamate/glutamine (Glx) turnover curves to determine rate constants of metabolite turnover and to aid in the visualization of metabolite time courses.

RESULTS

Deuterium label was incorporated into Glx from BHB metabolism through the tricarboxylic acid (TCA) cycle, with an increase in the level of [4,4]-² H 2 -Glx (d 2 -Glx) over time and reaching a quasi-steady state concentration of ∼0.6 ± 0.1 mM following 30 min of infusion. Complete oxidative metabolic breakdown of d 4 -BHB also resulted in the formation of semi-heavy water (HDO), with a four-fold (10.1 to ∼42.1 ± 7.3 mM) linear (R² = 0.998) increase in its concentration by the end of infusion. The rate constant of Glx turnover from d 4 -BHB metabolism was determined to be 0.034 ± 0.004 min^-1 .

CONCLUSION

² H-MRS can be used to monitor the cerebral metabolism of BHB with its deuterated form by measuring the downstream labeling of Glx. The integration of² H-MRS with deuterated BHB substrate provides an alternative and clinically promising MRS tool to detect neurometabolic fluxes in healthy and disease conditions.

Authors:

• Soni ND
• Swain A
• Jacobs P
• Juul H
• Armbruster R
• Nanga RPR
• Nath K
• Wiers C
• Detre J
• Reddy R

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i recently started getting closer to my coworke(what i thought was best friend) because i went through a breakup and she did as well. She gives me comfort when i’m feeling lonely and grieving my ex. I do the same and recently i confessed to her i had feelings for her or that I was catching them. I felt bad not being honest with her and i knew that i had to hell her when i realized that I was crushing on her. she has taught me a lot about anger management and communication because when i look at her i melt. i want to do better as she has helped me get a soft spot in my heart. during this i miss my ex. she is hurting for other reasons that is i’ll not share but. our dynamic was always about being there for each other. maybe we were each others rebounds or maybe we are just at a dissatisfaction from what we want from one another. anyways… here’s the problem. when she’s sad i ask her why and i try to listen but i think that is not what she likes and when i asked her she said she didn’t like it. i slowly began to stop asking but it is weird how we went from telling each other everything and hanging out everyday, to now it being her feel bothered when having too open up. i noticed she removed me from her throwaway instagram and unfollowed me. she also turned off her read notifications. i wouldn’t have noticed if i didn’t check but i when i didI told her whatever it was she could of told me. she then says she feels smothered… she wants space. now what do i do? i have had a hard time accepting rejection in the past but she taught me a lot about communication and now i can be more rational when dealing with rejection. but do i continue the friendship? is it doomed? i don’t know because this is a first. we have always been platonic but these situations are so similar to a relationship.

I have been having heart problems this month (March) my heart rate will jump up to like 150-160, this happens randomly and it makes it hard to work as I have to sit down and if I am not at work it makes it unsafe to drive and is extremely exhausting. I am a ssv and I missed work on the 5th for this and I was the opening shift (I truly do not recall this). Monday, the 27th, I had to call out because I woke up not feeling well, I couldn't get my SM to answer the phone so I try to go into work, I am sobbing, and end up throwing up on the side of the road. I call everyone, my SM 10 times, other shifts, facilities (I know they can't help), finally I call another store to get the DM's number. I turned around bc obviously I threw up and by their own symptom checker I would fail.... So I call my DM, I am just coming down from crying, I am tired, sick, and he seems nice enough. So I don't think much of this, until I come in today, my manager pulls me in the back and tells me that the DM wanted her to have a conversation with me about FMLA, or Disability, or demoting etc., until I get better. I understand this and was doing it already but then she says that the DM told her that if I want to move up (I have aspirations of being ASM/SM) that I won't be able to do that if I keep getting sick and missing work. I said is that not illegal to discriminate based on health and disability issues and my manager says yes, but then continues to tell me that I should look into FMLA etc so that I am covered. She says that patterns of absence can be documented and result in separation, she says like 25% of missed shifts equals a pattern and I said have I gotten to 25%? and she goes "well I don't know," and I am not good at math but 2 absences in the whole of March when I work 5 days a week is not 25%. So I am super confused and honestly feeling really defeated and discriminated against. I don't really know what to do, I almost walked out today but I can barely afford to work there let alone afford to leave.

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I (F21) was diagnosed with anxiety and depression at 13 and up until getting into college I started to learn how my medication was supposed to help and make me feel. I found it wasn’t working the way it was supposed to and that with the number of symptoms to other disorders such as ADHD I must have been misdiagnosed.
I would tell her this, saying the two roommates I had who majored in psychology told me I show signs of ADHD, one even mentioned autism. She didn’t seem to listen much because she didn’t try to work out what was going on with me. And it runs in my family meaning it’s a large possibility I have it. I kept doing more research because I am so tired of running into negative episodes where I feel like every mental disorder I possibly have are all triggered. I looked more into autism. I told her about it and she told me no I can’t have it because I don’t have clapping hands. Didn’t ask me why I thought it was a possibility or anything. Just right away shut it down with that comment.
It makes me so angry because the more I talk to people who have it and research I do, the more I find it’s most certainly a possibility. I mean I love numbers and patterns which is why algebra is my favorite subject and why I have to read every license plate and find what the letters could be abbreviating (apparently that’s not a normal thing they everyone does??). I am pretty dang sensitive to noise. I get into really obsessive episodes with random things (like listening to the same song 50 times before changing it) that don’t last very long, and I get a little too aggressive too easily and often hit my laptop, desk, stomp my feet, or tense my muscles to not do that. I have tics like little hums and kinda clicking like sounds. I HAVE to have the same morning and night routine otherwise I get stressed out and upset and I have a lot of sensory issues with touch like certain fabrics drive me insane. I struggle with eye contact, especially with more authority figures, like how much eye contact is too much? When am I supposed to look away? And I never understand social cues, most metaphors and too many jokes, and I can’t seem to make a single friend.
She referred me to someone for a full mental health evaluation in May. If this isn’t autism or ADHD, I really hope they can help me because this is exhausting. I just wanted to rant to people who would probably understand, thank you for reading if you did.

Hey guys. So yeah I’m here because half of my left labia tore off. It’s not a joke. When I gave birth they told me I had 3 first degree very MINOR TEARS. I didn’t look downstairs for 8 weeks as I was terrified of the aftermath of birth. When I finally looked down there, half of my labia was gone.
I’m literally confused because I don’t know where my labia went. How on earth did they stitch something that clearly fell off? My only next option is to get a labiaplasty and I want to try and seek some compensation from my hospital but I feel like I won’t be taken seriously.
Like dude, half of my labia is missing. I know it’s just the outside and everything inside works fine… But this is gut wrenching. This is my BODY. I’m so f*cking hurt. They keep telling me it will look a bit funky even after the 8 weeks and to not expect it to look like this forever. I’m 4 months postpartum and I’m pretty sure I’m not gonna just grow back my missing labia piece.

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Hi throwaway account
I‘ve been diagnosed with CPSTD and I am seeing a therapist, over all I’m doing a lot better in life now but I’m finding it hard to deal with the effects of my mental health when most of my childhood I can’t remember. It‘s hard to explain so I’ll use an example
Whenever I would hug a male friend of mine my mind kinda screamed and tensed like it needed to get away. I didn’t know this was a thing until I tried to open up to him to deal with trust issues, you should’ve seen me I was shaking and needing reassurance like “tell me you won’t hurt me” and “I’m not hurting you by telling you this am I?”. Either way I stayed strong and played bored games to convince my brain I was safe. Afterwards that tensing didn’t happen and I felt great like resetting a broken bone. Now here’s the thing I know why I asked if I was hurting him because other people I opened up to couldn’t handle it and it made their stresses worse. I have no idea or memory of where the other two came from. I didn’t know those things were issues because I didn’t know that wasn’t normal and I had no bad memory associated with it.
The other half of this question is that some things I remember weren’t real. I vividly remember watching a TV show where near the end it was revealed they were in space the whole time. I asked friends about this show because I really liked it and they didn’t remember it, looking around on the internet it’s not real. That’s a small case but I remember organising a gang when I was small to go beat up a school bully, he did transfer but no one else remembers the violence.
So yeah, any advice on how to deal with effects of CPTSD when I don’t know where they came from or even if the things I do remember are real? I thought I needed to uncover what repressed memories I had in my childhood to properly deal with them but my therapist says I just need to manage the effects.

Some of my favorite games of all time are Half Life (all the games), Starcraft (both games, but moreso SC1/Brood War), and Beyond Good And Evil. I list these specifically because they are linear story based games that involve other sentient species as main/supporting cast. I do enjoy sci-fi in general (the aforementioned games, Firefly, Dune, Star Wars, Titanfall, etc). However I'm not really a fan of when things get to be too sci-fi...by this I mean when stuff all looks extremely stereotypical sci fi with either everything super smooth or super angular, chrome everywhere, etc. I like a bit a grit still (ie Firefly, Starcraft, or Half Life). A strong and colorful cast is important to me as well. If I don't find the characters interesting, I'll drop the game pretty quickly.
Some things I don't really love are LONG game (to me a long game is like 15+ hours, I know, my definition is on the shorter side), games with a lot of fillefluff content, open world games, and games that don't have a particularly interesting narrative (I know an "interesting" narrative is subjective, but try to work with me with this definition). I also *really dislike grinding in games to meet some arbitrary stat threshold in order to beat X enemy/boss/section.
When I say I don't enjoy fillefluff content, I don't mean strictly sidequesting. I'm fine with sidequesting if it is meaningful in a story/narrative way. I just hate random fetch quests, escort quests, etc.
Kinda thinking about trying Mass Effect and I've heard so many good things about the franchise, but I'm not really sure. Any insight? If it matters, I would likely be playing on PC.
Btw, I know my tastes are kind of...particular. Sorry if they are too vague or just outright strange. I appreciate anyone who takes the time to help!

So I had sex with a new partner that I knew for a while back in October and December. The first time in October, I started experiencing symptoms the next day, pain and soreness, mild burning, watery brown/yellow/grey discharge, waited a month to get tested for STDs, those came out negative, but got diagnosed with Bv, started taking medication right away, felt better in a week, now the second time which was in December, I told my partner to put a condom on which he did, maybe after 4 minutes, I felt him taking it off and he put it in quick and I stopped him. After that I cut him off, and that same day a few hours later I started experiencing same symptoms again. Now I went to the doctor after a month and got tested for STDs again which came out negative again, but got diagnosed visually with Bv, doctor also did a vaginitis + swab twice which came out negative for everything especially BV, so it was weird. Now a few weeks after that I started to feel the symptoms on and off. I kept getting tested, which everything came out negative. Now I started talking to my kids father and we were talking about getting back together so we got tested, came out negative. Now when we were about to have sex I told him to use a condom, he kept refusing but eventually did put it on, now a few minutes later he stopped and he said he was fixing the condom, i didn’t saw him do it but It felt different when he sticked it back in right away and I realized that he took it off the whole time and went raw. Now the next day I noticed he was being itchy in his pubic area and he would rub his penis a lot and saw red tiny dots on his penis head, he ended up going to the doctor a few days after that and got diagnosed with balanitis. And I went to the doctor also and got diagnosed with Bv again but it was once again weird because on my Bv tests they keep coming out negative, and when me and him would be done with treatment, and have sex again without a condom I would start to feel the same symptoms again but mild this time and he would also feel itchy again. WE are thinking about going to the doctor again, could this be another std I haven’t tested for?

My friend and I went at it again today, did maybe 5 matches, first 2 were the same crew, 1st time they got us with a cheesy strat of playing dumb but got a silent board while we were on angle, second time we knew what to expect and survived maybe 45 minutes before we agreed to just D20 roll and end the long battle, they won the roll, the next 3 were all ships with emissary 5 flags, who clearly played the game more than they have touched grass, one crew went by and got perfect snipes on both of us so we lost that one pretty quick, the next two were just fast sinks both hitting shots from where battle starts and landing two shots on wheel then on cannon killing both me and my crewmate, when they boarded us right at the end both times one was a gold skeleton curse dude and the other match it was ghost athena crew so we just gave up for the night cause it seems like once it gets close to midnight PST its pure sweats going for 1000 in their respective faction, so 5-loss streak with matchmaking putting us against progressively harder opponents, didn't even get a level (we are currently at 33 and 35 for athena). Really wishing there was some long super difficult PvE grind to get these curses at this point, just cause man are they a pain to do in PvP. Will probably keep doing them each night till we get 100 in both factions then be done with the mode.

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i truly don’t know if this is grued. i cried hard but tbh my chest feels better i can breathe and idk maybe she had a point this was a closure we needed. but it hurt in the moment but i didn’t feel anything when k asked her why. did she still love me. did she still think of me. did she want me. i asked her and even as i cried it didn’t hurt. i’ll always cry for her. i love her. i see her everywhere and anywhere i regret what i once told her. but i knew we weren’t meant to be so what do i want from her. what do i feel. was it just hard to let go. was she in the right to make the first steps. i told her i won’t contact her unless she does it first and k want to give her that space i want to give her the time to love me again but idk man i’m just stupid idek what i’m saying. i need help